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Crysta PGS Increase your chance of successful IVF

Pre-Implantation Genetic Screening to help you increase your chance of successful IVF by selecting genetically normal embryos.

Overview

An embryo screening (in IVF process) can analyse embryo’s genetic health and improve your chance of achieving a successfulpregnancy.

Preimplantation Genetic Screening (PGS)
PGS (widely known as aneuploidy screening) involves checking the chromosomes of embryos created by in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) for abnormalities. PGS gives information about embryos’ genetic health to select the best embryo for transfer and improve your chance of achieving a successful pregnancy.

Disclaimer - According to Government of India PCPNDT Act, PGS Genetic Testing shall not disclose any information regarding the sex of the foetus in the clinical report.

Why PGS ?

  • Aneuploidy is the main cause for embryo arrest, implantation failure, recurrent pregnancy loss and birth defects.
  • Aneuploidy rate is extremely high in IVF patients
  • Selection of chromosomally normal embryos for transfer by aneuploidy screening is primary focus of PGS.
  • Embryos may look ‘normal’ under the lab microscope, but even those that grow to blastocyst stage (day 5-6) might not have the right number of chromosomes.
  • Screening lets us handpick healthy embryos.

Who might be recommended ?

  • The woman is of advanced maternal age.
  • When there are incidences of frequent or multiple miscarriage or even planned pregnancy with IVF.
  • “Male factor Infertility”

How PGS works ?

  • A small sample of cell is removed fromthe outside layer of a blastocyst embryo
  • Cell thus obtained fromeach embryo are loaded into a small tube and sent to the reference laboratory for next generation sequencing.
  • Further the cells are analysed for intact 23 sets of chromosomes in them to confirm the embryo is genetically normal.
  • Will be advised for the appropriate cells to be transferred.

Goals of PGS

  • Reduced risk of miscarriage
  • More confidence in transferring a single embryo, avoiding health risks associated with twin or triplet pregnancies
  • Higher chance of pregnancy
  • Reduced number of IVF cycles needed to achieve pregnancy, potentially reducing the time to pregnancy and the costs of extra cycles