MAIN MENU
Liquid Biopsy

Oncocliffe offers high quality, accurate and reliable testing of Liquid biopsies

Overview

Oncocliffe Liquid Biopsy protocols target the cfDNA in blood which can be easily drawn from patients with minimal invasiveness (Liquid Biopsy) and can be used for diagnosis, prognosis, recurrence-risk prediction, or can be biopted at regular intervals to dynamically monitor disease progression, drug response and to customize cancer care. cfDNA assays also prove useful in detecting resistance mutations to tyrosine kinase inhibitors. Oncocliffe offers high quality, accurate and reliable testing of Liquid biopsies for identification of most common genetic alterations.

Test Details

A. Oncocliffe Pan Cancer Cell free Assay - 52 Genes

The Oncocliffe Pan Cancer cell-free assay is multibiomarker next-generation sequencing (NGS) assay that enable reliable detection of somatic mutations in plasma, for genes relevant to solid tumors.

Genes Covered

Genes CNV Fusions Extra
AKT1 CTNNB1 GNAQ NTRK1 CCND1 ALK Met Exon 14 skipping
ALKDDR2GNASNTRK3CCND2BRAF
APCEGFRHRASPDGFRACCND3ERG
ARERBB2IDH1PIK3CACDK4ETV1
ARAFERBB3IDH2PTENCDK6FGFR1
BRAFERGKITRAF1EGFRFGFR2
CCND1ESR1KRASRETERBB2FGFR3
CCND2ETV1MAP2K1ROS1FGFR1MET
CCND3FBXW7MAP2K2SF3B1FGFR2NTRK1
CDK4FGFR1METSMAD4FGFR3NTRK3
CDK6FGFR2MTORSMOMETRET
CHEK2FGFR3MYCTP53MYCROS1
FLT3FGFR4NRASGNA11

B. Oncocliffe Lung Cancer Liquid Biopsy panel

Genes Covered : ALK, BRAF, EGFR, ERBB2, KRAS, MAP2K1, MET, NRAS, PIK3CA, RET, ROS1 and TP53 (169 Hot spots and 49 Fusions of ALK, RET, ROS1 and CNV of MET).

C. Oncocliffe Breast Cancer Liquid Biopsy Panel

Genes Covered : AKT1, CCND1, EGFR, ERBB2, ERBB3, ESR1, FBXW7, FGFR1, KRAS, PIK3CA, SF3B1 and TP53 (152 Hot spot mutations and CNVs of CCND1, ERBB2, FGFR1).

D. Oncocliffe Colon Cancer Liquid Biopsy Panel

Genes Covered : AKT1, APC, BRAF, CTNNB1, EGFR, ERBB2, FBXW7, GNAS, KRAS, MAP2K1, NRAS, PIK3CA, SMAD4 and TP53 (236 Hotspots)

Sample Type

10 ml whole blood in Streck Tube


Transportation

4-8℃


TAT

3-4 weeks

Tests

Test Code Description Methodology TAT Sample Details Transportation
RCL508 Oncocliffe Liquid biopsy Pan cancer cell free assay- 52 genes (12 CNV genes, 96 fusions from 12 genes, MET exon 14 skipping) NGS 30 Days Whole Blood in Streck (BCT -Cell free DNA)Tube 9-10 ml Whole Blood in BCT tube
RCL509 Oncocliffe Liquid Biopsy- Lung cf Total Nucleic acid assay (11 Gens, 169 Hot spots and 49 Fusions of ALK, RET, ROS1 and CNV of MET) NGS 30 Days Whole Blood in Streck (BCT -Cell free DNA)Tube 9-10 ml Whole Blood in BCT tube
RCL510 Oncocliffe Liquid Biopsy - Breast cfDNA assay (10 Genes, 152 Hot spot mutations and CNVs of CCND1, ERBB2, FGFR1 ) NGS 30 Days Whole Blood in Streck (BCT -Cell free DNA)Tube 9-10 ml Whole Blood in BCT tube
RCL511 Oncocliffe Liquid Biopsy- Colon cfDNA assay (14 genes, 236 Hot spots) NGS 30 Days Whole Blood in Streck (BCT -Cell free DNA)Tube 9-10 ml Whole Blood in BCT tube
RCL512 Oncocliffe Liquid Biopsy- Hot Spot Mutations Panel (SNP only) 50 Genes NGS 30 Days Whole Blood in Streck (BCT -Cell free DNA)Tube 9-10 ml Whole Blood in BCT tube